La Liga, also commonly known as Primera División, is the most prominent Spanish football league system. Since its inception in 1929, 62 teams have competed in the league. Real Madrid has won the most championships with 36 La Liga titles.
The Spanish powerhouse La Liga, which remained the top league in Europe in each of the seven years from 2013 to 2019 as per the UEFA‘s league coefficient rankings, has provided a platform to several football icons in the history of the sport. Many have prolifically featured in the league.
Here are the players with most appearances in La Liga:
Andoni Zubizarreta- 622

Andoni Zubizarreta is one of the two players with most appearances in La Liga with 622 matches. The goalkeeper featured for clubs including Athletic Bilbao (169), Barcelona (301) and Valencia (152) from 1981 to 1998 in the Spanish league.
Joaquín– 622

Another player who has featured the most in La Liga is Joaquín with 622 appearances. He has played in the colours of Real Betis (407), Valencia (158) and Málaga (57). He has scored 70 goals in the league. He scored most goals for Betis at 32.
Raúl García- 609

Raúl García has 609 appearances in La Liga in his two decades of career at the league. He has played for clubs including Osasuna (101), Atlético Madrid (216) and Athletic Bilbao (292). The midfielder has 112 goals in the league, scoring the most for Athletic Bilbao at 65. He scored 20 goals for Osasuna and 25 for Atlético Madrid.
Raúl González Blanco- 550

Raúl González Blanco, known mononymously as Raúl, made 550 appearances for Real Madrid. He has played only in the colours of Real Madrid in the league from 1994 to 2010. He has scored 228 goals in the league.
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Eusebio Sacristán Mena

Eusebio Sacristán Mena, known simply as Eusebio, made 543 appearances in the Spanish League. He has featured the most for Valladolid with 246 appearances. He then went on to play for Atlético Madrid (27), Barcelona (203) and Celta Vigo (67). The midfielder scored 36 goals in the league playing from 1983 to1987. He scored the most for Valladolid with 18 goals. He netted 14 for Barcelona, three for Atlético Madrid, one for Celta.